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undefined   What is pTeroPure®?
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pTeroPure®, also known as pterostilbene (pronounced tero-STILL-bean), is closely related to resveratrol. Although similar in structure, pterostilbene offers the following advantages over resveratrol:

  • Superior bioavailability
  • Significantly longer half-life
  • Greater cellular uptake
  • Greater oral absorption and metabolic stability
Why is pterostilbene so interesting?

Pterostilbene activates a very specific nuclear receptor known as PPAR-alpha. Nuclear receptors are proteins that activate gene expression. PPAR-alpha is activated during fasting states or the prolonged periods without food. Once activated, PPAR-alpha controls lipid metabolism among other essential functions.

Fasting and calorie restriction have been heavily researched as a possible approach to extend lifespan in lower mammals. In this regard, pterostilbene may offer pro-longevity benefits by activating the PPAR-alpha nuclear receptor.

Claims Supported by Science

  • Promotes healthy cellular function with powerful antioxidant activities1*
  • Promotes healthy blood flow and circulation 2*
  • Promotes cognitive function as demonstrated in animal models 3, 4*
  • Supports cardiovascular health as demonstrated in cellular and animal models 5, 1*

 

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* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
  1. McCormack, D. and D. McFadden, A review of pterostilbene antioxidant activity and disease modification. Oxid Med Cell Longev, 2013. 2013: p. 575482.
  2. Riche, D.M., et al., Pterostilbene on metabolic parameters: a randomized, double-blind, and placebocontrolled trial. Evid Based Complement Alternat Med, 2014. 2014: p. 459165
  3. Poulose, S.M., et al., Effects of pterostilbene and resveratrol on brain and behavior. Neurochem Int, 2015. 89: p. 227-33.
  4. Chang, J., et al., Low-dose pterostilbene, but not resveratrol, is a potent neuromodulator in aging and Alzheimer’s disease. Neurobiol Aging, 2012. 33(9): p. 2062-71.
  5. Kosuru, R., et al., Promising therapeutic potential of pterostilbene and its mechanistic insight based on preclinical evidence. Eur J Pharmacol, 2016. 789: p. 229-43.