||What is pTeroPure®?
pTeroPure®, also known as pterostilbene (pronounced tero-STILL-bean), is closely related to resveratrol. Although similar in structure, pterostilbene offers the following advantages over resveratrol:
- Superior bioavailability
- Significantly longer half-life
- Greater cellular uptake
- Greater oral absorption and metabolic stability
Why is pterostilbene so interesting?
Pterostilbene activates a very specific nuclear receptor known as PPAR-alpha. Nuclear receptors are proteins that activate gene expression. PPAR-alpha is activated during fasting states or the prolonged periods without food. Once activated, PPAR-alpha controls lipid metabolism among other essential functions.
Fasting and calorie restriction have been heavily researched as a possible approach to extend lifespan in lower mammals. In this regard, pterostilbene may offer pro-longevity benefits by activating the PPAR-alpha nuclear receptor.
Claims Supported by Science
- Promotes healthy cellular function with powerful antioxidant activities1*
- Promotes healthy blood flow and circulation 2*
- Promotes cognitive function as demonstrated in animal models 3, 4*
- Supports cardiovascular health as demonstrated in cellular and animal models 5, 1*
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* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
- McCormack, D. and D. McFadden, A review of pterostilbene antioxidant activity and disease modification. Oxid Med Cell Longev, 2013. 2013: p. 575482.
- Riche, D.M., et al., Pterostilbene on metabolic parameters: a randomized, double-blind, and placebocontrolled trial. Evid Based Complement Alternat Med, 2014. 2014: p. 459165
- Poulose, S.M., et al., Effects of pterostilbene and resveratrol on brain and behavior. Neurochem Int, 2015. 89: p. 227-33.
- Chang, J., et al., Low-dose pterostilbene, but not resveratrol, is a potent neuromodulator in aging and Alzheimer’s disease. Neurobiol Aging, 2012. 33(9): p. 2062-71.
- Kosuru, R., et al., Promising therapeutic potential of pterostilbene and its mechanistic insight based on preclinical evidence. Eur J Pharmacol, 2016. 789: p. 229-43.